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Spotlight:

Articles of Significant Interest Selected from This Issue by the Editors
J. Virol. 2008 82: 9807. [Full Text] [PDF] FREE [Reprints and Permissions]  

Pathogenesis and Immunity:

Henry Radziewicz, Chris C. Ibegbu, Huiming Hon, Melissa K. Osborn, Kamil Obideen, Mohammad Wehbi, Gordon J. Freeman, Jeffrey L. Lennox, Kimberly A. Workowski, Holly L. Hanson, and Arash Grakoui

Impaired Hepatitis C Virus (HCV)-Specific Effector CD8⁺ T Cells Undergo Massive Apoptosis in the Peripheral Blood during Acute HCV Infection and in the Liver during the Chronic Phase of Infection
J. Virol. 2008 82: 9808-9822. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jessica K. Roth-Cross, Susan J. Bender, and Susan R. Weiss

Murine Coronavirus Mouse Hepatitis Virus Is Recognized by MDA5 and Induces Type I Interferon in Brain Macrophages/Microglia
J. Virol. 2008 82: 9829-9838. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Kevin R. Mott, David UnderHill, Steven L. Wechsler, and Homayon Ghiasi

Lymphoid-Related CD11c⁺ CD8⁺ Dendritic Cells Are Involved in Enhancing Herpes Simplex Virus Type 1 Latency
J. Virol. 2008 82: 9870-9879. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Carlos Barcia, Aurora Gomez, Vicente de Pablos, Emiliano Fernández-Villalba, Chunyan Liu, Kurt M. Kroeger, Javier Martín, Andrés Fernández Barreiro, Maria G. Castro, Pedro R. Lowenstein, and Maria-Trinidad Herrero

CD20, CD3, and CD40 Ligand Microclusters Segregate Three-Dimensionally In Vivo at B-Cell-T-Cell Immunological Synapses after Viral Immunity in Primate Brain
J. Virol. 2008 82: 9978-9993. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Min Hua Luo, Philip H. Schwartz, and Elizabeth A. Fortunato

Neonatal Neural Progenitor Cells and Their Neuronal and Glial Cell Derivatives Are Fully Permissive for Human Cytomegalovirus Infection
J. Virol. 2008 82: 9994-10007. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Gamal Badr, Nathalie Bédard, Mohamed S. Abdel-Hakeem, Lydie Trautmann, Bernard Willems, Jean-Pierre Villeneuve, Elias K. Haddad, Rafick P. Sékaly, Julie Bruneau, and Naglaa H. Shoukry

Early Interferon Therapy for Hepatitis C Virus Infection Rescues Polyfunctional, Long-Lived CD8⁺ Memory T Cells
J. Virol. 2008 82: 10017-10031. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Nicole M. Bouvier, Anice C. Lowen, and Peter Palese

Oseltamivir-Resistant Influenza A Viruses Are Transmitted Efficiently among Guinea Pigs by Direct Contact but Not by Aerosol
J. Virol. 2008 82: 10052-10058. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Cindy L. Sood, Jerrold M. Ward, and Bernard Moss

Vaccinia Virus Encodes I5, a Small Hydrophobic Virion Membrane Protein That Enhances Replication and Virulence in Mice
J. Virol. 2008 82: 10071-10078. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Karim Sacre, Stéphanie Nguyen, Claire Deback, Guislaine Carcelain, Jean-Paul Vernant, Véronique Leblond, Brigitte Autran, and Nathalie Dhedin

Expansion of Human Cytomegalovirus (HCMV) Immediate-Early 1-Specific CD8⁺ T Cells and Control of HCMV Replication after Allogeneic Stem Cell Transplantation
J. Virol. 2008 82: 10143-10152. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Vaishali Chaudhuri, Marvin Sommer, Jaya Rajamani, Leigh Zerboni, and Ann M. Arvin

Functions of Varicella-Zoster Virus ORF23 Capsid Protein in Viral Replication and the Pathogenesis of Skin Infection
J. Virol. 2008 82: 10231-10246. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Frederic Bibollet-Ruche, Brett A. McKinney, Alexandra Duverger, Frederic H. Wagner, Aftab A. Ansari, and Olaf Kutsch

The Quality of Chimpanzee T-Cell Activation and Simian Immunodeficiency Virus/Human Immunodeficiency Virus Susceptibility Achieved via Antibody-Mediated T-Cell Receptor/CD3 Stimulation Is a Function of the Anti-CD3 Antibody Isotype
J. Virol. 2008 82: 10271-10278. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ikuo Tsunoda, Tomoko Tanaka, and Robert S. Fujinami

Regulatory Role of CD1d in Neurotropic Virus Infection
J. Virol. 2008 82: 10279-10289. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Manoj Thapa and Daniel J. J. Carr

Herpes Simplex Virus Type 2-Induced Mortality following Genital Infection Is Blocked by Anti-Tumor Necrosis Factor Alpha Antibody in CXCL10-Deficient Mice
J. Virol. 2008 82: 10295-10301. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Montse Gustems, Andreas Busche, Martin Messerle, Peter Ghazal, and Ana Angulo

In Vivo Competence of Murine Cytomegalovirus under the Control of the Human Cytomegalovirus Major Immediate-Early Enhancer in the Establishment of Latency and Reactivation
J. Virol. 2008 82: 10302-10307. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

M. G. Lyman, D. Curanovic, A. D. Brideau, and L. W. Enquist

Fusion of Enhanced Green Fluorescent Protein to the Pseudorabies Virus Axonal Sorting Protein Us9 Blocks Anterograde Spread of Infection in Mammalian Neurons
J. Virol. 2008 82: 10308-10311. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

W. W. Laegreid, M. L. Clawson, M. P. Heaton, B. T. Green, K. I. O'Rourke, and D. P. Knowles

Scrapie Resistance in ARQ Sheep
J. Virol. 2008 82: 10318-10320. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Genome Replication and Regulation of Viral Gene Expression:

G. J. Seo, L. H. L. Fink, B. O'Hara, W. J. Atwood, and C. S. Sullivan

Evolutionarily Conserved Function of a Viral MicroRNA
J. Virol. 2008 82: 9823-9828. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Naveen Kumar, Zhong-tao Xin, Yuhong Liang, Hinh Ly, and Yuying Liang

NF-B Signaling Differentially Regulates Influenza Virus RNA Synthesis
J. Virol. 2008 82: 9880-9889. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Vanessa Wilhelmi, Christian O. Simon, Jürgen Podlech, Verena Böhm, Torsten Däubner, Simone Emde, Dennis Strand, Angélique Renzaho, Niels A. W. Lemmermann, Christof K. Seckert, Matthias J. Reddehase, and Natascha K. A. Grzimek

Transactivation of Cellular Genes Involved in Nucleotide Metabolism by the Regulatory IE1 Protein of Murine Cytomegalovirus Is Not Critical for Viral Replicative Fitness in Quiescent Cells and Host Tissues
J. Virol. 2008 82: 9900-9916. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Wuxiang Guan, Fang Cheng, Yuko Yoto, Steve Kleiboeker, Susan Wong, Ning Zhi, David J. Pintel, and Jianming Qiu

Block to the Production of Full-Length B19 Virus Transcripts by Internal Polyadenylation Is Overcome by Replication of the Viral Genome
J. Virol. 2008 82: 9951-9963. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Sanggu Kim, Namshin Kim, Beihua Dong, David Boren, Serena A. Lee, Jaydip Das Gupta, Christina Gaughan, Eric A. Klein, Christopher Lee, Robert H. Silverman, and Samson A. Chow

Integration Site Preference of Xenotropic Murine Leukemia Virus-Related Virus, a New Human Retrovirus Associated with Prostate Cancer
J. Virol. 2008 82: 9964-9977. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Klemens Ruprecht, Humberto Ferreira, Aline Flockerzi, Silke Wahl, Marlies Sauter, Jens Mayer, and Nikolaus Mueller-Lantzsch

Human Endogenous Retrovirus Family HERV-K(HML-2) RNA Transcripts Are Selectively Packaged into Retroviral Particles Produced by the Human Germ Cell Tumor Line Tera-1 and Originate Mainly from a Provirus on Chromosome 22q11.21
J. Virol. 2008 82: 10008-10016. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Rodion Gorchakov, Natalia Garmashova, Elena Frolova, and Ilya Frolov

Different Types of nsP3-Containing Protein Complexes in Sindbis Virus-Infected Cells
J. Virol. 2008 82: 10088-10101. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Yan Yang, MinKyung Yi, David J. Evans, Peter Simmonds, and Stanley M. Lemon

Identification of a Conserved RNA Replication Element (cre) within the 3D^pol-Coding Sequence of Hepatoviruses
J. Virol. 2008 82: 10118-10128. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Hiro-oki Iwakawa, Hiroyuki Mizumoto, Hideaki Nagano, Yuka Imoto, Kazuma Takigawa, Siriruk Sarawaneeyaruk, Masanori Kaido, Kazuyuki Mise, and Tetsuro Okuno

A Viral Noncoding RNA Generated by cis-Element-Mediated Protection against 5'3' RNA Decay Represses both Cap-Independent and Cap-Dependent Translation
J. Virol. 2008 82: 10162-10174. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Meike Hass, Michaela Lelke, Carola Busch, Beate Becker-Ziaja, and Stephan Günther

Mutational Evidence for a Structural Model of the Lassa Virus RNA Polymerase Domain and Identification of Two Residues, Gly1394 and Asp1395, That Are Critical for Transcription but Not Replication of the Genome
J. Virol. 2008 82: 10207-10217. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

María-Eugenia Gas, Diego Molina-Serrano, Carmen Hernández, Ricardo Flores, and José-Antonio Daròs

Monomeric Linear RNA of Citrus Exocortis Viroid Resulting from Processing In Vivo Has 5'-Phosphomonoester and 3'-Hydroxyl Termini: Implications for the RNase and RNA Ligase Involved in Replication
J. Virol. 2008 82: 10321-10325. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Virus-Cell Interactions:

James B. Stanton, Donald P. Knowles, Katherine I. O'Rourke, Lynn M. Herrmann-Hoesing, Bruce A. Mathison, and Timothy V. Baszler

Small-Ruminant Lentivirus Enhances PrP^Sc Accumulation in Cultured Sheep Microglial Cells
J. Virol. 2008 82: 9839-9847. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Matthew J. Trifilo, Manuel Sanchez-Alavez, Laura Solforosi, Joie Bernard-Trifilo, Stefan Kunz, Dorian McGavern, and Michael B. A. Oldstone

Scrapie-Induced Defects in Learning and Memory of Transgenic Mice Expressing Anchorless Prion Protein Are Associated with Alterations in the Gamma Aminobutyric Acid-Ergic Pathway
J. Virol. 2008 82: 9890-9899. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Nick van Buuren, Brianne Couturier, Yue Xiong, and Michele Barry

Ectromelia Virus Encodes a Novel Family of F-Box Proteins That Interact with the SCF Complex
J. Virol. 2008 82: 9917-9927. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Koichi Watashi, Mohammad Khan, Venkat R. K. Yedavalli, Man Lung Yeung, Klaus Strebel, and Kuan-Teh Jeang

Human Immunodeficiency Virus Type 1 Replication and Regulation of APOBEC3G by Peptidyl Prolyl Isomerase Pin1
J. Virol. 2008 82: 9928-9936. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jennifer A. Regan and Laimonis A. Laimins

Bap31 Is a Novel Target of the Human Papillomavirus E5 Protein
J. Virol. 2008 82: 10042-10051. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Roza Izmailyan and Wen Chang

Vaccinia Virus WR53.5/F14.5 Protein Is a New Component of Intracellular Mature Virus and Is Important for Calcium-Independent Cell Adhesion and Vaccinia Virus Virulence in Mice
J. Virol. 2008 82: 10079-10087. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Robert McMahon and Derek Walsh

Efficient Quiescent Infection of Normal Human Diploid Fibroblasts with Wild-Type Herpes Simplex Virus Type 1
J. Virol. 2008 82: 10218-10230. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

R. Jeremy Nichols, Eleni Stanitsa, Bethany Unger, and Paula Traktman

The Vaccinia Virus Gene I2L Encodes a Membrane Protein with an Essential Role in Virion Entry
J. Virol. 2008 82: 10247-10261. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Structure and Assembly:

Gregory Bird, Malinda O'Donnell, Junona Moroianu, and Robert L. Garcea

Possible Role for Cellular Karyopherins in Regulating Polyomavirus and Papillomavirus Capsid Assembly
J. Virol. 2008 82: 9848-9857. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Annett Stange, Daniel Lüftenegger, Juliane Reh, Winfried Weissenhorn, and Dirk Lindemann

Subviral Particle Release Determinants of Prototype Foamy Virus
J. Virol. 2008 82: 9858-9869. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Nathaniel W. Martinez, Xiaoxiao Xue, Reem G. Berro, Geri Kreitzer, and Marilyn D. Resh

Kinesin KIF4 Regulates Intracellular Trafficking and Stability of the Human Immunodeficiency Virus Type 1 Gag Polyprotein
J. Virol. 2008 82: 9937-9950. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Benjamin J. Chen, George P. Leser, David Jackson, and Robert A. Lamb

The Influenza Virus M2 Protein Cytoplasmic Tail Interacts with the M1 Protein and Influences Virus Assembly at the Site of Virus Budding
J. Virol. 2008 82: 10059-10070. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Helga Eizert, Pálma Bander, Péter Bagossi, Tamás Sperka, Gabriella Miklóssy, Péter Boross, Irene T. Weber, and József Tözsér

Amino Acid Preferences of Retroviral Proteases for Amino-Terminal Positions in a Type 1 Cleavage Site
J. Virol. 2008 82: 10111-10117. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Kristen M. Stewart-Maynard, Margareta Cruceanu, Fei Wang, My-Nuong Vo, Robert J. Gorelick, Mark C. Williams, Ioulia Rouzina, and Karin Musier-Forsyth

Retroviral Nucleocapsid Proteins Display Nonequivalent Levels of Nucleic Acid Chaperone Activity
J. Virol. 2008 82: 10129-10142. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Christina Bourne, Sejin Lee, Bollu Venkataiah, Angela Lee, Brent Korba, M. G. Finn, and Adam Zlotnick

Small-Molecule Effectors of Hepatitis B Virus Capsid Assembly Give Insight into Virus Life Cycle
J. Virol. 2008 82: 10262-10270. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Philomena Ostapchuk and Patrick Hearing

Adenovirus IVa2 Protein Binds ATP
J. Virol. 2008 82: 10290-10294. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Vaccines and Antiviral Agents:

Elena Gustchina, Carole A Bewley, and G. Marius Clore

Sequestering of the Prehairpin Intermediate of gp41 by Peptide N36^Mut(e,g) Potentiates the Human Immunodeficiency Virus Type 1 Neutralizing Activity of Monoclonal Antibodies Directed against the N-Terminal Helical Repeat of gp41
J. Virol. 2008 82: 10032-10041. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Miki Kawada, Tetsuo Tsukamoto, Hiroyuki Yamamoto, Nami Iwamoto, Kyoko Kurihara, Akiko Takeda, Chikaya Moriya, Hiroaki Takeuchi, Hirofumi Akari, and Tetsuro Matano

Gag-Specific Cytotoxic T-Lymphocyte-Based Control of Primary Simian Immunodeficiency Virus Replication in a Vaccine Trial
J. Virol. 2008 82: 10199-10206. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Cellular Response to Infection:

Kenji Takeuchi, Takayuki Komatsu, Yoshinori Kitagawa, Kiyonao Sada, and Bin Gotoh

Sendai Virus C Protein Plays a Role in Restricting PKR Activation by Limiting the Generation of Intracellular Double-Stranded RNA
J. Virol. 2008 82: 10102-10110. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Lüder Wiebusch, Anke Neuwirth, Linus Grabenhenrich, Sebastian Voigt, and Christian Hagemeier

Cell Cycle-Independent Expression of Immediate-Early Gene 3 Results in G₁ and G₂ Arrest in Murine Cytomegalovirus-Infected Cells
J. Virol. 2008 82: 10188-10198. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Gene Delivery:

Laura Menotti, Arianna Cerretani, Hartmut Hengel, and Gabriella Campadelli-Fiume

Construction of a Fully Retargeted Herpes Simplex Virus 1 Recombinant Capable of Entering Cells Solely via Human Epidermal Growth Factor Receptor 2
J. Virol. 2008 82: 10153-10161. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Transformation and Oncogenesis:

Liliana Terrin, Jessica Dal Col, Enrica Rampazzo, Paola Zancai, Moreno Pedrotti, Grazia Ammirabile, Stefano Bergamin, Silvana Rizzo, Riccardo Dolcetti, and Anita De Rossi

Latent Membrane Protein 1 of Epstein-Barr Virus Activates the hTERT Promoter and Enhances Telomerase Activity in B Lymphocytes
J. Virol. 2008 82: 10175-10187. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Genetic Diversity and Evolution:

Alessio Lorusso, Nicola Decaro, Pepijn Schellen, Peter J. M. Rottier, Canio Buonavoglia, Bert-Jan Haijema, and Raoul J. de Groot

Gain, Preservation, and Loss of a Group 1a Coronavirus Accessory Glycoprotein
J. Virol. 2008 82: 10312-10317. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Letters to the Editor:

Jing Qin Wu, Bin Wang, and Nitin K. Saksena

Transitory Viremic Surges in a Human Immunodeficiency Virus-Positive Elite Controller Can Shift the Cellular Transcriptome Profile: a Word of Caution for Microarray Studies
J. Virol. 2008 82: 10326-10327. [Full Text] [PDF] [Reprints and Permissions]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.